By David Roshan De Silva-Thompson
We aim to use titanium doped phosphate glass as a platform for culturing microunits of tissue engineered bone using scalable reactor technology. The role of titanium doped bioactive glass is being widely studied as an implantable scaffold material for bone defects. Illustrating many benefits such as its ability to degrade in vivo whilst remaining non cyto-toxic at certain concentrations coupled with its maintained structural stablity, confirms its potential as an attractive alternative for bone regeneration. Understanding their impact and effect in culture, along with their ability to be used at reactor scale provides the rationale behind the project.
We aim to use titanium doped phosphate glass as a platform for culturing microunits of tissue engineered bone using scalable reactor technology. The role of titanium doped bioactive glass is being widely studied as an implantable scaffold material for bone defects. Illustrating many benefits such as its ability to degrade in vivo whilst remaining non cyto-toxic at certain concentrations coupled with its maintained structural stablity, confirms its potential as an attractive alternative for bone regeneration. Understanding their impact and effect in culture, along with their ability to be used at reactor scale provides the rationale behind the project.