We are very pleased to have won a large grant with ReNeuron Ltd and the Cell & Gene Therapy Catapult to develop an exosome manufacturing pathway. Exosomes are a novel class of therapeutics, produced and released by stem cells. The £2.5M grant builds on out existing collaboration successes with ReNeuron in the area of exosome purification and formulation. In this new grant, we will use novel microfluidic bioreactors that can screen 24 different input conditions in a total working volume of 120 microlitres to optimise cell culture processes and then, working with CGTC, validate these using bench- and industry-scale technologies for large scale manufacture. The project starts May 2016.
|